本文发表在 rolia.net 枫下论坛These data should be considered in the context of vaccination status of the population groupsshown in the rest of this report. The vaccination status of cases, inpatients and deaths is not themost appropriate method to assess vaccine effectiveness and there is a high risk ofmisinterpretation. Vaccine effectiveness has been formally estimated from a number of differentsources and is described earlier in this report.In the context of very high vaccine coverage in the population, even with a highly effectivevaccine, it is expected that a large proportion of cases, hospitalisations and deaths would occurin vaccinated individuals, simply because a larger proportion of the population are vaccinatedthan unvaccinated and no vaccine is 100% effective. This is especially true because vaccinationhas been prioritised in individuals who are more susceptible or more at risk of severe disease.Individuals in risk groups may also be more at risk of hospitalisation or death due to nonCOVID-19 causes, and thus may be hospitalised or die with COVID-19 rather than because ofCOVID-19.The case rates in the vaccinated and unvaccinated populations are crude rates that do not takeinto account underlying statistical biases in the data. There are likely to be systematicdifferences in who chooses to be tested and the COVID risk of people who are vaccinated.These biases become more evident as more people are vaccinated and the differencesbetween the vaccinated and unvaccinated population become systematically different in waysthat are not accounted for without undertaken formal analysis of vaccine effectiveness as ismade clear.NIMS is used as a denominator because it is a database of named individuals eligible forvaccination in which there is a record of each individual’s vaccination status更多精彩文章及讨论，请光临枫下论坛 rolia.net
