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转: 疫苗引发心肌炎证据实锤了

刚刚看到NEJM这个paper

详细描述了疫苗导致心肌炎机理:S蛋白诱发抗体脱靶攻击了自体蛋白,导致心肌细胞炎性反应。paper也说了这个是否产生自体免疫抗体也是运气和基因有关。

(我支持科学,自己也打了n针疫苗,但是科学新发现我还是认真学习,不会根据自己立场忽视科学)

每个人打不打疫苗,booster,都需要自己做好risk reward analysis

​​​​​​​https://www.nejm.org/doi/full/10.1056/NEJMc2205667

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Replies, comments and Discussions:

  • 枫下家园 / 医药保健 / 转: 疫苗引发心肌炎证据实锤了 +10

    刚刚看到NEJM这个paper

    详细描述了疫苗导致心肌炎机理:S蛋白诱发抗体脱靶攻击了自体蛋白,导致心肌细胞炎性反应。paper也说了这个是否产生自体免疫抗体也是运气和基因有关。

    (我支持科学,自己也打了n针疫苗,但是科学新发现我还是认真学习,不会根据自己立场忽视科学)

    每个人打不打疫苗,booster,都需要自己做好risk reward analysis

    ​​​​​​​https://www.nejm.org/doi/full/10.1056/NEJMc2205667

    • 好像半年前就实锤了。比例不大,风险不小。 +1
      • 疫苗厂早就知道了,能骗就先骗着,骗不过了再承认,反正也没有任何惩罚。 +9
        • 成人COVID-19的心脏表现 +1
          • 以色列研究了20万未接种者,并没有发现新冠患者会增加心肌炎或心包炎的发病率。 +1
            Myocarditis and pericarditis are potential post-acute cardiac sequelae of COVID-19 infection, arising from adaptive immune responses. We aimed to study the incidence of post-acute COVID-19 myocarditis and pericarditis. Retrospective cohort study of 196,992 adults after COVID-19 infection in Clalit Health Services members in Israel between March 2020 and January 2021. Inpatient myocarditis and pericarditis diagnoses were retrieved from day 10 after positive PCR. Follow-up was censored on 28 February 2021, with minimum observation of 18 days. The control cohort of 590,976 adults with at least one negative PCR and no positive PCR were age- and sex-matched. Since the Israeli vaccination program was initiated on 20 December 2020, the time-period matching of the control cohort was calculated backward from 15 December 2020. Nine post-COVID-19 patients developed myocarditis (0.0046%), and eleven patients were diagnosed with pericarditis (0.0056%). In the control cohort, 27 patients had myocarditis (0.0046%) and 52 had pericarditis (0.0088%). Age (adjusted hazard ratio [aHR] 0.96, 95% confidence interval [CI]; 0.93 to 1.00) and male sex (aHR 4.42; 95% CI, 1.64 to 11.96) were associated with myocarditis. Male sex (aHR 1.93; 95% CI 1.09 to 3.41) and peripheral vascular disease (aHR 4.20; 95% CI 1.50 to 11.72) were associated with pericarditis. Post COVID-19 infection was not associated with either myocarditis (aHR 1.08; 95% CI 0.45 to 2.56) or pericarditis (aHR 0.53; 95% CI 0.25 to 1.13). We did not observe an increased incidence of neither pericarditis nor myocarditis in adult patients recovering from COVID-19 infection.
        • 强卖假冒伪劣产品,不受任何惩罚,这钱赚得爽啊 +4